Plasma C-Reactive Protein Levels Among Children With Sleep-Disordered Breathing

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Plasma C-reactive protein levels among children with sleep-disordered breathing.

INTRODUCTION Levels of C-reactive protein (CRP), an important serum marker of inflammation with major implications for cardiovascular morbidity and atherogenesis, are elevated among adult patients with sleep-disordered breathing (SDB). We hypothesized that elevated CRP plasma levels would also be present among children with SDB. METHODS Eighty-one children (mean age: 9.3 +/- 3.7 years) underw...

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Variation of C-reactive protein levels in adolescents: association with sleep-disordered breathing and sleep duration.

BACKGROUND There is increasing evidence that sleep-disordered breathing (SDB) is an independent risk factor for cardiovascular disease (CVD) in adults. C-reactive protein (CRP), a marker of systemic inflammation, is an important predictor of future cardiovascular events. The goal of this study was to quantify the associations of SDB, sleep duration, and CRP in adolescents to better understand t...

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Plasma adhesion molecules in children with sleep-disordered breathing.

STUDY OBJECTIVES To determine whether childhood sleep-disordered breathing (SDB) is associated with elevated levels of plasma adhesion molecules. DESIGN Prospective, observational study. SETTING Sleep Medicine Center of Kosair Children's Hospital. PARTICIPANTS Thirty-nine children with SDB (apnea-hypopnea index [AHI] > 5/h), 47 children with mild SDB (AHI 1 to 5/h), and 42 healthy control...

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Morning levels of fibrinogen in children with sleep-disordered breathing.

Elevated fibrinogen level is a predictor of cardiovascular disease in adults, and it is associated with sleep-disordered breathing. Levels of fibrinogen in adults are affected by other co-existing cardiovascular risk factors, which are not usually present in children. To investigate the association between fibrinogen and sleep-disordered breathing, a case-control study was carried out in childr...

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C-reactive protein is associated with sleep disordered breathing independent of adiposity.

STUDY OBJECTIVES It is well established that medical conditions such as obesity and cardiovascular disease are associated with increased levels of inflammatory biomarkers such as C-reactive protein (CRP). Prior studies have produced inconsistent results regarding the association between sleep disordered breathing (SDB) and CRP, possibly due to the confounding effects of obesity or medical comor...

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ژورنال

عنوان ژورنال: PEDIATRICS

سال: 2004

ISSN: 0031-4005,1098-4275

DOI: 10.1542/peds.113.6.e564